Description

Buy Cathine Cas 492-39-7

Cathine, also known as D-norpseudoephedrine or as (+)-norpseudoephedrine, is a psychoactive drug of the phenethylamine and amphetamine groups which acts as a stimulant. Along with cathinone, it is found naturally in Catha edulis (khat), and contributes to the overall effects of the plant.^[3] Cathine has approximately 7 to 10% of the potency of amphetamine.^[3] Like amphetamines, cathinone and ephedrine, cathine acts as a norepinephrine releasing agent (NRA).^[3] It also acts as a dopamine releasing agent (DRA).^[3][4]

Monoamine release by cathine and related agents (EC₅₀Tooltip half maximal effective concentration, nM)

Compound	NETooltip Norepinephrine	DATooltip Dopamine	5-HTTooltip Serotonin	Ref
Dextroamphetamine (S(+)-amphetamine)	6.6–7.2	5.8–24.8	698–1,765	[5][6]
S(–)-Cathinone	12.4	18.5	2,366	[7]
Ephedrine ((–)-ephedrine)	43.1–72.4	236–1,350	>10,000	[5]
(+)-Ephedrine	218	2,104	>10,000	[5][7]
Dextromethamphetamine (S(+)-methamphetamine)	12.3–13.8	8.5–24.5	736–1,292	[5][8]
Levomethamphetamine (R(–)-methamphetamine)	28.5	416	4,640	[5]
(+)-Phenylpropanolamine ((+)-norephedrine)	42.1	302	>10,000	[7]
(–)-Phenylpropanolamine ((–)-norephedrine)	137	1,371	>10,000	[7]
Cathine ((+)-norpseudoephedrine)	15.0	68.3	>10,000	[7]
(–)-Norpseudoephedrine	30.1	294	>10,000	[7]
(–)-Pseudoephedrine	4,092	9,125	>10,000	[7]
Pseudoephedrine ((+)-pseudoephedrine)	224	1,988	>10,000	[7]
Notes: The smaller the value, the more strongly the drug releases the neurotransmitter. The assays were done in rat brain synaptosomes and human potencies may be different. See also Monoamine releasing agent § Activity profiles for a larger table with more compounds. Refs:[9][10]

Cathine is one of the four stereoisomers of phenylpropanolamine (PPA). The World Anti-Doping Agency's list of prohibited substances (used for the Olympic Games among other athletic events) bans cathine in concentrations of over 5 micrograms per milliliter in urine. Cathine is a Schedule III drug under the Convention on Psychotropic Substances.^[11] In the United States, it is classified as a Schedule IV controlled substance.^[12] In Australia, Cathine is officially a schedule 4 drug prescription only, but is not available or approved for any medical use.

In Hong Kong, cathine is regulated under Schedule 1 of Hong Kong's Chapter 134 Dangerous Drugs Ordinance. Unlawful possession is punishable by severe fines and imprisonment. Ephedra, found in many Ephedraceae species, is a Chinese and Western herb that contains, among other amphetamines, D-norpseudoephedrine. In the National Birth Defects Prevention Study, which included 18,438 women from 10 states from 1999 to 2003, 1.3% of women reported using ephedra during pregnancy. During the trial, five cases of anencephaly were born to women who used ephedra, however there was no statistically significant association to women not using ephedra (odds ratio 2.8, confidence interval 1.0–7.3).^[13] A small study of 642 participants in Yemen found that among pregnant women who chewed khat (containing D-norpseudoephedrine) there was no increased risk of stillbirth or congenital malformations.^[14] Among lactating women who chew khat, D-norpseudoephedrine is found in breastmilk.^[15]

• L-Norpseudoephedrine, the enantiomer
• Methcathinone
• Ephedra sinica ("Ephedra")
• Ephedrine
• Pseudoephedrine
• Methamphetamine

• Cathine (CAS 492-39-7)

  Cayman Chemical

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  Cathine is a natural phenethylamine from the Khat (C. edulis) plant. While biochemically and behaviorally cathinone-like, cathine is substantially less potent ...Read more

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  Cathine - Cayman Chemical Forensics

  Cambridge Bioscience

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  Cathine ; Supplier: Cayman Chemical Forensics ; Size: 1 mg ; CAS Number: 492-39-7 ; Purity: ≥98% ; Formulation: A crystalline solid.Read more

  Cathine [A crystalline solid]

  LGC Standards

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  CAS Number. 492-39-7. Product Format. Neat. Molecular Formula. C9 H13 N O. Molecular Weight. 151.21. Product Categories. Reference Materials from Cayman ...Read more

  Cathine

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  Cathine. CAS: 492-39-7. Ref. TR-P839580. 5mg. 97.00€VAT not included. Add to cart ... Cathine (6CI); (+)-Norpseudoephedrine; (+)-Pseudonorephedrin; (+) ...Read more

  CATHINE HYDROCHLORIDE | 492-39-7

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  CAS No. 492-39-7 ; Chemical Name: CATHINE HYDROCHLORIDE ; CBNumber: CB4116082 ; Molecular Formula: C9H13NO ; Molecular Weight: 151.21.Read more

  CAS 492-39-7

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  Find 492-39-7 and related products for scientific research at Merck. ... Cathine hydrochloride. Synonym(s): threo-2-Amino-1-hydroxy-1-phenyl propane ...Read more

  CAS 492-39-7: Cathine

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  Cathine agit comme un stimulant du système nerveux central, présentant des effets similaires à ceux des amphétamines, bien qu'il soit généralement considéré ...Read more

  Cathine | CAS 492-39-7

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  Aperçu clinique. La cathine (numéro CAS 492-39-7), également connue sous le nom de d-norpseudoéphédrine ou (+)-norpseudoéphédrine, est un composé psychoactif ...Read more

  Cathine | Drug Information, Uses, Side Effects, Chemistry

  PharmaCompass – Grow Your Pharma Business Digitally

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  Closely related to ephedrine, cathinone and other amphetamines, it may contribute to the stimulant effect of Catha edulis.Read more