Description
Buy Pholedrine Cas 370-14-9
Pholedrine, also known as
4-hydroxy-N-methylamphetamine and sold under the brand names
Paredrinol,
Pulsotyl, and
Veritol among others, is a
sympathomimetic drug used in
topical eye drops to
dilate the pupil.
[1][2][3] It can be used to diagnose
Horner's syndrome.
[3]
In 2004, it remained marketed only in
Germany.
[1][needs update]
Pharmacology
Pharmacodynamics
Pholedrine is described as a
sympathomimetic,
antihypotensive, and
ephedrine-like agent.
[4][1][5]
Chemistry
Pholedrine, also known as 4-hydroxy-
N-methylamphetamine, is a
substituted phenethylamine and
amphetamine derivative.
[4][1] It is
structurally related to
methamphetamine (
N-methylamphetamine),
norpholedrine (4-hydroxyamphetamine),
oxilofrine (4,β-dihydroxy-
N-methylamphetamine), and
tyramine (4-hydroxyphenethylamine).
It is used
pharmaceutically as the
sulfate salt.
[1][4]
The predicted
log P of pholedrine ranges from 1.12 to 1.7.
[2][6][7]
History
Pholedrine was
synthesized by 1951.
[4]
Society and culture
Names
Pholedrine is the
generic name of the drug and its
INNTooltip International Nonproprietary Name,
BANTooltip British Approved Name, and
DCFTooltip Dénomination Commune Française, while
foledrina is its
DCITTooltip Denominazione Comune Italiana.
[4][1][5] The drug has been sold under brand names including
Pholedrin Liquidum,
Pholedrin-Longo-Isis,
Presoitan,
Veritain, and
Veritol among others.
[4][1]
Other drugs
Pholedrine (4-hydroxymethamphetamine) is also a major
metabolite of
methamphetamine.
Pholedrine | CAS# 370-14-9 (free base) | Autonomic Agent
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Pholedrine is an Autonomic Agent. It is a a sympathomimetic vasoconstrictive drug which has been used to treat chronic hypotension.
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Pholedrine | Sympathomimetic Agent | MedChemExpress
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CAS 370-14-9: (±)-Pholedrine
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(
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p-Hydroxymethamphetamine
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p-Hydroxymethamphetamine analytical standard, for drug analysis; CAS Number: 370-14-9; EC Number: 206-725-0; Synonyms: Pholderin at Sigma-Aldrich.
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