Description
Buy Aleph Cas 61638-07-1
Aleph, or
ALEPH-1, also known as
DOT or
para-DOT or as
4-methylthio-2,5-dimethoxyamphetamine, is a
psychedelic drug of the
phenethylamine,
amphetamine, and
DOx families.
[1] It is one of the
Aleph series of compounds.
[1]
Use and effects
In his book
PiHKAL (
Phenethylamines I Have Known and Loved),
Alexander Shulgin lists Aleph's dose range as 5 to 10
mg
orally and its
duration as 6 to 8
hours.
[1] The effects of Aleph have been reported to include simple tasks feeling "alien", intense intellectual stimulation, impairment, a sensation of pleasant physical warmth, and an
afterglow including feelings of
empathy for everything.
[1]
Interactions
Pharmacology
Pharmacodynamics
Aleph is known to be a
partial agonist of the
serotonin 5-HT2A receptor (
EC50Tooltip half-maximal effective concentration = 10–66
nM;
EmaxTooltip maximal efficacy = 114–191%).
[2][3]
It has weak
MAO-A inhibitory activity with an
IC50Tooltip half-maximal inhibitory concentration of 5.2
μM.
[4] For comparison,
amphetamine has an IC
50 of 11
μM and
4-methylthioamphetamine (4-MTA) has a value of 0.2
μM.
[4]
Chemistry
Synthesis
The
chemical synthesis of Aleph has been described.
[1]
Derivatives
Derivatives of Aleph include
Aleph-2,
Aleph-4,
Aleph-6, and
Aleph-7.
[1] The Aleph series of compounds are the
DOx or
amphetamine analogues of
2C-T,
2C-T-2,
2C-T-4,
2C-T-6, and
2C-T-7, respectively.
[1]
History
Aleph was first tested by
Alexander Shulgin in 1975.
[1] It was first described in the
scientific literature by Shulgin and
David E. Nichols in 1976.
[5][6] Its properties and effects in humans were described by them in 1978.
[7] Subsequently, the drug was described in greater detail by Shulgin in his 1991 book
PiHKAL (
Phenethylamines I Have Known and Loved).
[1]
Society and culture
Names
Aleph was named by
Alexander Shulgin, who named it after the
first letter of the
Hebrew alphabet.
[1] Another earlier name of the drug is
para-DOT.
[1][7]
Legal status
Canada
Aleph is a
controlled substance in
Canada under phenethylamine blanket-ban language.
[8]
United States
In the
United States, Aleph is a
Schedule 1 controlled substance as a
positional isomer of
2C-T-4 and
2C-T-7.
[9]
See also
- DOx (psychedelics)
- 2C-T
-
Aleph
Chemical Route
https://chemicalroute.com › Phenethylamine
Cas number
61638-07-1. Formula C12H19NO2S. Molar Mass 241.35 g·mol
−1. Purity ... Store in a well-ventilated place. Keep container tightly closed. P405 ...
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2,5-DIMETHOXY-4-METHYLTHIOAMPHETAMINE
National Institutes of Health (NIH) | (.gov)
https://gsrs.ncats.nih.gov › ginas › app › beta › substances
CAS,
61638-07-1, PRIMARY, None, View. WIKIPEDIA,
ALEPH (PSYCHEDELIC), PRIMARY, None, View. PUBCHEM, 143828, PRIMARY, None, View. FDA UNII, C9ZVF4O01N, PRIMARY
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Aleph (psychedelic)
Wikipedia
https://en.wikipedia.org › wiki › Aleph_(psychedelic)
Aleph, or ALEPH-1, also known as DOT or para-DOT or as 4-methylthio-2,5-dimethoxyamphetamine,
is a psychedelic drug of the phenethylamine, amphetamine, ...
Read more
Application of High Resolution Mass Spectrometry for the ...
CORE
https://files01.core.ac.uk › download › pdf
by JZ Seither · Cited by 1 — CAS/Chemspider numbers, and monoisotopic mass for each compound. A ...
61638-07-1. C12H19NO2S. Phenethylamine. 2,5-Dimethoxy-4 ...
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271 pages
aleph
Wikidata
https://www.wikidata.org › wiki
Aleph-1; 4-methylthio-2,5-dimethoxyamphetamine; para-DOT; 1-[2,5-dimethoxy-4 ... https://commonchemistry.
cas.org/detail?
cas_rn=
61638-07-1 · ChemSpider ID.
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Aleph (psychedelic)
wikidoc
https://www.wikidoc.org › index.php › Aleph_(psychede...
4 Sept 2012 — Aleph, or 2,5-dimethoxy-4-methylthioamphetamine,
is a psychedelic hallucinogenic drug and a substituted amphetamine of the phenethylamine ...
Read more
2,5-Dimethoxy-4-methylthioamphetamine - PubChem
National Institutes of Health (NIH) | (.gov)
https://pubchem.ncbi.nlm.nih.gov › compound › 2_5-...
61638-07-1; Aleph (psychedelic); C9ZVF4O01N; J273.478H. View More... Molecular Weight. 241.35 g/mol. Computed by PubChem 2.2 (PubChem release 2024.11.20). Dates.
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DOx
Wikipedia
https://en.wikipedia.org › wiki › DOx
DOx is a chemical class of substituted amphetamine derivatives featuring methoxy groups at the 2- and 5- positions of the phenyl ring.
Read more
Forskrift om narkotika (narkotikaforskriften)
Lovdata
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14 Feb 2013 — Det er stoffnavnet i listen som er avgjørende, mens
CAS-numrene er ment som tilleggsinformasjon for å lettere kunne identifisere stoffene.
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