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Buy Lys-MDMA Cas 2763054-67-5
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Buy Lys-MDMA Cas 2763054-67-5

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Buy Lys-MDMA Cas 2763054-67-5

Lys-MDMA, or lysine-MDMA, also known as N-(L-lysinamidyl)-MDMA, is an intended prodrug of MDMA which was being investigated for possible use as a pharmaceutical drug in the treatment of psychiatric disorders.[2][3][4][5][6] Structurally, lys-MDMA is to MDMA as lisdexamfetamine is to dextroamphetamine[5][4] As of August 2024, a phase 1 clinical trial comparing MDMA, MDA, lys-MDMA, and lys-MDA has been conducted and completed.[2][3][6] Lys-MDMA was being developed by MindMed.[3][6] The published phase 1 clinical trial unexpectedly found that lys-MDMA does not convert into MDMA in humans and is completely inactive.[1] This is in contrast to lisdexamfetamine and lys-MDA, where are converted into dextroamphetamine and MDA, respectively.[1] The lack of conversion was attributed to steric hindrance caused by the N-methyl group of lys-MDMA.[1]

See also

  • Substituted methylenedioxyphenethylamine
  • List of investigational hallucinogens and entactogens
  • Lys-MDA
  • Lisdexamfetamine
  • DA-Phen
  • Phenatine
  • MiHKAL
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