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Buy α-Pyrrolidinohexiophenone (α-PHP- A-PHP- Aphp- alpha-PHP- α-Pyrrolidinohexanophenone- PV-7) Cas 13415-86-6
home | Buy α-Pyrrolidinohexiophenone (α-PHP- A-PHP- Aphp- alpha-PHP- α-Pyrrolidinohexanophenone- PV-7) Cas 13415-86-6

Buy α-Pyrrolidinohexiophenone (α-PHP- A-PHP- Aphp- alpha-PHP- α-Pyrrolidinohexanophenone- PV-7) Cas 13415-86-6

Description

α-Pyrrolidinohexiophenone (α-PHPA-PHPAphpalpha-PHPα-PyrrolidinohexanophenonePV-7) is a synthetic stimulant drug of the cathinone class developed in the 1960s[2] which has been reported as a novel designer drug.[3][4][5][6][7]

Similar chemical compounds

α-Pyrrolidinohexiophenone is a longer chain homologue of α-PVP, having an extra carbon on the alkyl side chain. Regarding the potency of alpha-PHP in the brain, chemist Michael H. Baumann of the Designer Drug Research Unit (established by Baumann[8]) of the National Institute on Drug Abuse stated: "alpha-PHP might be even more potent than alpha-PVP"; this statement is based on laboratory tests of chemical reactivity.[9] Pyrovalerone is a structural isomer of alpha-PHP.[10]

Pharmacology

Pharmacological Receptor Activity Profile of Novel Pyrovalerones Compared to Reference Amphetamines [11]
Drug NET DAT SERT DAT/SERT Ratio
⍺-PVP 0.02 (0.01‒0.05) 0.03 (0.02‒0.04) 279 (209‒372) >1000
⍺-PHP 0.06 (0.03‒0.12) 0.06 (0.05‒0.08) 245 (173‒348) >1000
MDMA 0.41 (0.33‒0.52) 13 (11‒16) 1.6 (1.2‒2.2) 0.12 (0.08‒0.20)
Amphetamine 0.07 (0.05‒0.1) 1.3 (0.8‒2.0) 45 (24‒85) 35 (12‒106)

Legality

The President of the Republic of Italy classified cathinone and all structurally derived analogues (including pyrovalerone analogues) as narcotics in January 2012.[12][13] Sweden's public health agency suggested to classify α-PHP as narcotic on June 1, 2015.[14] As of October 2015, α-PHP is a controlled substance in China.[15] In December 2019, the UNODC announced scheduling recommendations placing Alpha-PHP into Schedule II.[16] As of 29 October 2021, α-PHP has been banned in the Netherlands under the 1971 Vienna Convention on Psychotropic Substances.[17] In the US, a-PHP is a Schedule I controlled substance as of 2022.[18]

See also

  • α-PHiP
  • α-PHPP
  • α-PBP
  • α-PPP
  • A-PCyP
  • 4F-PHP
  • 4-Cl-PHP
  • 4-Methyl-α-PHP
  • Prolintane
  • Pyrovalerone
  • MDPV
  • MDPHP
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