Description

Buy 2-Fluoromethcathinone (2-FMC) Cas 1186137-35-8

2-Fluoromethcathinone (2-FMC), also known as 2-flephedrone, is a psychostimulant and designer drug of the cathinone family.^[1][2][3][4] It acts as a dopamine and norepinephrine releasing agent (NDRA).^[4] The drug has an EC₅₀Tooltip half-maximal effective concentration for dopamine release of 48.7 nM and induces 85% release of norepinephrine at a concentration of 10 μM.^[4] For comparison, the EC₅₀ values of methcathinone are 49.9 nM for dopamine release and 22.4 nM for norepinephrine release and it induces 100% release of norepinephrine at a concentration of 10 μM.^[4][5] Hence, compared to methcathinone, 2-FMC appears to be relatively more selective or efficacious for induction of dopamine release over norepinephrine release.^[4][5] It is notable in this regard that selective dopamine releasing agents are largely unknown.^[6][4]

• 3-Methoxymethcathinone
• 3-Fluoromethcathinone
• 4-Fluoromethcathinone (flephedrone)
• 2-Fluoromethamphetamine