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Buy 2-Naphthylmethcathinone (BMAPN) Cas 109453-73-8
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Buy 2-Naphthylmethcathinone (BMAPN) Cas 109453-73-8

Description

===

2-Naphthylmethcathinone (BMAPN), also known as βk-methamnetamine, is a stimulant drug of the cathinone and naphthylaminopropane families. It inhibits dopamine reuptake and has rewarding and reinforcing properties in animal studies.[1][2] It is banned under drug analogue legislation in a number of jurisdictions. The drug was at one point marketed under the name NRG-3, although only a minority of samples of substances sold under this name have been found to actually contain BMAPN, with most such samples containing mixtures of other cathinone derivatives.[3][4]
Monoamine release of BMAPN and related agents (EC50Tooltip Half maximal effective concentration, nM)
Compound NETooltip Norepinephrine DATooltip Dopamine 5-HTTooltip Serotonin Ref
d-Amphetamine 6.6–10.2 5.8–24.8 698–1,765 [5][6][7][8][9]
Naphthylaminopropane (NAP; PAL-287) 11.1 12.6 3.4 [10][7]
d-Methamphetamine 12.3–14.3 8.5–40.4 736–1,292 [5][11][7][9]
Methylnaphthylaminopropane (MNAP; PAL-1046) 34 10 13 [12][13]
l-Methcathinone 13.1 14.8 1,772 [14][8]
2-Naphthylmethcathinone (BMAPN; βk-MNAP) 94% at 10 μM 34 27 [15][16]
d-Ethylamphetamine 28.8 44.1 333.0 [17][18]
Ethylnaphthylaminopropane (ENAP; PAL-1045) 137 46 a 12 a [12]
Phenmetrazine 29–50.4 70–131 7,765–>10,000 [19][7][20][21]
Naphthylmetrazine (PAL-704) 203 111 RI (105) [21]
Notes: The smaller the value, the more strongly the drug releases the neurotransmitter. The assays were done in rat brain synaptosomes and human potencies may be different. See also Monoamine releasing agent § Activity profiles for a larger table with more compounds. Footnotes: a ENAPTooltip Ethylnaphthylaminopropane is a partial releaser of serotonin (EmaxTooltip maximal efficacy = 66%) and dopamine (Emax = 78%). Refs: [22][23]

See also

  • 1-Naphthylmethcathinone (AMAPN)
  • βk-Ephenidine
  • Methamnetamine
  • Methylnaphthidate
  • Methylone
  • Naphyrone
  • WF-23
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