Methedrone (para-methoxymethcathinone, 4-methoxymethcathinone, bk-PMMA, PMMC, methoxyphedrine, 4-MeOMC) is a recreational drug of the cathinonechemical class.[2] Chemically, methedrone is closely related to para-methoxymethamphetamine (PMMA), methylone and mephedrone. Methedrone received media attention in 2009 after the death of two young Swedish men. In both cases toxicology analysis showed methedrone was the only drug present in both men during the time of their overdose and subsequent deaths.[3][4]
Uses
Dosage
There is little information available about how Methedrone is dosed. According to users, a single dose of Methedrone varies from 50 to 500 mg with effects lasting 45 minutes to two hours. There are at least two cases known of fatal intoxications with Methedrone. In the first case, the postmortem femoral blood sample of the patient contained a concentration of 8.4 μg/g Methedrone, the patient died 16 hours after consumption (with polysubstance use detected). In the second body the concentration in the femoral blood sample was 9.6 μg/g, with Methedrone being the only toxic compound detected. The scientific investigation[3] of these cases suggests that the Methedrone alone was responsible for these deaths and that the concentrations in the femoral blood represent the fatal levels of methedrone. These studies show that the therapeutic index (or safety ratio) is low compared to other illegal drugs like Amphetamine. A fatal dose is likely to be around 8 μg/g whereas the dose among users varies from 0.1 to 4.8 μg/g blood according to studies.[3]
Adverse effects
Anecdotal and case reports of human use of "bath salts", such as methedrone, suggest that these substances produce powerful psychological effects. These psychological effects include psychotic behavior, paranoia, delusions, hallucinations and also self-injury.[5]
There is very little known of the physical effects of methedrone in humans, but studies to the effects of methedrone in mice show that it produces a significant increase in circling, beam breaks and hyperactivity. Furthermore, the mice also showed a significant increase in salivation, head weaving and stimulation. Methedrone is currently a legal drug in many jurisdictions, however studies show that it shares major pharmacological properties with drugs that have been banned, such as mephedrone and methylone. Also, the effects of Methedrone are very similar to the effects of banned drugs in mice.[5] This suggests that Methedrone may be just as harmful as most commonly found Illicit drugs.
The health risks associated with methedrone are mostly unknown, but are expected to be similar to other cathinones.[6] Methedrone was almost immediately withdrawn from sale by initial vendors after reports of adverse health effects.[citation needed] Some amphetamineanalogs containing a para-methoxy group are known to cause severe hyperthermia and even death due to concurrent MAOI and monoamine releasing action.[7]
AI Overview
Mephedrone (4-MMC) is a synthetic stimulant drug from the cathinone class, often marketed as a "legal high" or "bath salt"
. It is a controlled substance in many jurisdictions due to its potential for abuse, health risks, and psychoactive effects, which are similar to MDMA and amphetamines.
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Legal and Safety Warning
Controlled Substance: Mephedrone is banned or restricted in many countries (e.g., UK, EU, Australia, USA) under laws controlling new psychoactive substances (NPS).
Health Hazards: Use of 4-MMC can lead to serious adverse health effects, including severe addiction, acute toxicity, high blood pressure, and tremors.
Purity Concerns: While some samples show high purity, others contain unknown impurities or other synthetic substances.
Observatoire français des drogues et des tendances addictives +4
Information on Purchasing The search results do not provide legitimate retailers for purchasing 4-MMC, as it is largely prohibited. It is commonly found in illicit or "grey" markets.
United Nations Office on Drugs and Crime +1
Risks of Online Purchasing: Online sources claiming to sell such compounds, particularly from platforms offering "fast delivery" and "confidentiality," are often associated with illicit activities and are high-risk for scams or legal repercussions.
Detection: It can be detected in biological samples for up to 3 days after use.
National Institutes of Health (.gov) +2
Alternatives Due to the legal risks and safety hazards associated with 4-MMC, engaging with such substances is not recommended. For information regarding mental health, addiction support, or drug education, consult local health authorities.
Mephedrone - Wikipedia
Mephedrone, also known as 4-methylmethcathinone, 4-MMC, or 4-methylephedrone, is a synthetic stimulant drug belonging to the amphe...
Wikipedia
Mephedrone - Alcohol and Drug Foundation
6 Jun 2025 — Mephedrone (4-methylmethcathinone) is an empathogen-stimulant drug, which means it speeds up the messages travelling between the b...
Alcohol and Drug Foundation
TECHNICAL REPORT ON MEPHEDRONE - OFDT
15 Jul 2010 — Analysis of seized and purchased mephedrone has shown that it is generally of high purity (>95%). However, some samples of mephedr...
Observatoire français des drogues et des tendances addictives
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United Nations Office on Drugs and Crime
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530-54-1. Methylone, β k-MDMA. 1-(1,3-benzodioxol-5-yl)-2-(methylamino)-1 ... 4-MMC (mephedrone). 177.2. 9.70. 58.1, 77.0, 91.1, 119.1. N. -methylmephedrone.Read more
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by C Kelleher · 2011 · Cited by 54 — CAS #: 530-54-1. Methedrone is also known ... Dargan PI (2010) Recreational use of mephedrone 4-Methylmethcathinone (4-MMC) with associated.Read more
Methedrone
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https://en.wikipedia.org › wiki › Methedrone
Methedrone is a recreational drug of the cathinone chemical class. Chemically, methedrone is closely related to para-methoxymethamphetamine (PMMA), ...Read more
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4-MMC. MDPV bk-MDMA. 4-MEC. 4-FMC. N o of re ports. 1. 4-MMC; Mephedrone (4-methylmethcathinone). 68. 2. MDPV; 3,4-Methylenedioxypyrovalerone. 61. 3. bk-MDMA; ...Read more
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Le choix de ces paramètres dans un cas précis doit tenir compte de la drogue concernée et des moyens disponibles. ... 4-MMC (méphédrone). 177,2. 9,70. 58,1; 77,0; ...Read more
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Méphédrone et autres dérivés synthétiques de la cathinone
Confusingly there is a less common drug called Methedrone (bk-PMeoMA, 4 meo methcathinone, 530-54-1) which is very similar but is reputedly more cocaine-esque.Read more
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