Description
Buy N-Ethylpentylone (β-keto-ethylbenzodioxolylpentanamine- βk-ethyl-K- βk-EBDP- ephylone) Cas 727641-67-0
N-Ethylpentylone (
β-keto-ethylbenzodioxolylpentanamine,
βk-ethyl-K,
βk-EBDP,
ephylone) is a
substituted cathinone and
stimulant drug which was developed in the 1960s.
[2][3]
It has been reported as a novel
designer drug in several countries including the United Kingdom,
[4] South Africa,
[5] New Zealand,
[6] the United States,
[7] and Australia.
[8] In 2018,
N-ethylpentylone was the most common drug of the cathinone class to be identified in
Drug Enforcement Administration seizures.
[9]
Adverse effects
N-Ethylpentylone has been reported to cause lethal
heart palpitations and
hallucinations.
[10] It has been linked to a number of overdose deaths
[11][7] and hospitalisations,
[12][13] and has increasingly been mis-sold as
MDMA.
[14]
Pharmacology
N-Ethylpentylone is primarily a mixed
norepinephrine reuptake inhibitor and
dopamine reuptake inhibitor. It binds to transporters with
IC50 values of 37 nM (
dopamine transporter), 105 nM (
norepinephrine transporter) and 383 nM (
serotonin transporter).
[15] The methylenedioxy ring-substitution provides a higher potency at inhibiting serotonin reuptake than its analogue
N-ethylpentedrone.
[16] N-Ethylpentylone is also a low-
potency serotonin 5-HT2A receptor agonist, with an
EC50Tooltip half-maximal effective concentration of 5,200
nM.
[17]
In vivo studies in mice demonstrated that acute intraperitoneal administration of N-ethylpentylone induced an
increase in locomotor activity,
anxiolytic effects but also an
aggressive behaviour as well as social exploration deficits. Repeated exposure to N-ethylpentylone induced hyperthermia, anorexia and rewarding effects. During withdrawal after repeated administration, depression-like symptoms, hyperlocomotion, and a decrease of social exploration were observed.
[16][18]
Society and culture
Legal status
- In the United States, N-ethylpentylone is a Schedule I controlled substance since June 2018.[19]
- In Taiwan, N-ethylpentylone is a controlled substance under Taiwan's Controlled Drugs Act since Dec 2017.[20]
- In the Netherlands it has been added to the Opium Law on July 1 2025.[21]
See also
- Substituted methylenedioxyphenethylamine
- 5-Methylethylone
- Dipentylone
- Ethyl-K
- Eutylone
- Methylenedioxypyrovalerone (MDPV)
- N-Ethylhexedrone
- N-Ethylhexylone
- N-Ethylheptylone
- Pentylone
- Isohexylone
-
N-Ethylpentylone
Wikipedia
https://en.wikipedia.org › wiki › N-Ethylpentylone
N-Ethylpentylone (β-keto-ethylbenzodioxolylpentanamine, βk-ethyl-K, βk-EBDP, ephylone) is a substituted cathinone and stimulant drug which was developed in the
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N-ETHYLPENTYLONE (Street Names
DEA Diversion Control Division (.gov)
https://www.deadiversion.usdoj.gov › n-ethylpen...
N-Ethylpentylone is chemically known as 1-(1,3- benzodioxol-5-yl)-2-(ethylamino)pentan-1-one. The. CAS number for N-ethylpentylone is 727641-67-0. The ...
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Missing: keto- ethylbenzodioxolylpentanamine- βk- K- EBDP-
Substance Details N-Ethylnorpentylone
United Nations Office on Drugs and Crime
https://www.unodc.org › LSS › Substance › Details
N-Ethylnorpentylone ; 1-(benzo[d][1,3]dioxol-5-yl)-2-(ethylamino)pentan-1-one · Synthetic cathinones · Stimulants · 727641-67-0.
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Missing: (β- keto- ethylbenzodioxolylpentanamine- K-
N-Ethylpentylone | C14H19NO3 | CID 57359308 - PubChem
National Institutes of Health (NIH) | (.gov)
https://pubchem.ncbi.nlm.nih.gov › compound › N-Eth...
N-ethylpentylone is a DEA Schedule I controlled substance. Substances in the DEA Schedule I have no currently accepted medical use in the United States.
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Missing: keto- ethylbenzodioxolylpentanamine- βk-
N-ETHYLPENTYLONE-D5 HCL | E-130-1ML | SUPELCO
Scientific Laboratory Supplies (SLS) Ltd
https://www.scientificlabs.co.uk › product
N-Ethylpentylone, also known as Ephylone, is a stimulant and designer drug found in "bath salts". These synthetic cathinones offer recreational uses that mimic ...
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Missing: (β- keto- ethylbenzodioxolylpentanamine- βk- K- EBDP- Cas 727641-67-0
N-Ethylpentylone
iiab.me
http://medbox.iiab.me › wikipedia_en_medicine_2019-12
N-Ethylpentylone. N-Ethylpentylone (β-keto-ethylbenzodioxolylpentanamine, βk-ethyl-K, βk-EBDP, ephylone) is a substituted cathinone and stimulant drug which ...
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Best Price Safe Delivery N-Ethylpentylone CAS 727641-67 ...
Tradeindia
https://www.tradeindia.com › ... › chemical intermediates
Best Price Safe Delivery
N-ethylpentylone Cas 727641-67-0 In Stock. Price: Get Latest Price. In Stock. Product Overview.
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Missing: keto- ethylbenzodioxolylpentanamine- βk- K- EBDP- ephylone)
N-ethylpentylone
Wikidata
https://www.wikidata.org › wiki
4 Nov 2025 — N-ethylpentylone. chemical compound. ephylone; β-keto-ethylbenzodioxolylpentanamine; βk-ethyl-K; βk-EBDP. In more languages. Spanish. No label ...
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Analytical Quantification, Intoxication Case Series, and ...
National Institutes of Health (.gov)
https://pubmed.ncbi.nlm.nih.gov › ...
by JL Costa · 2019 · Cited by 64 — We present a validated method for quantifying
N-
ethylnorpentylone in human
case work. The drug is a psychomotor stimulant capable of inducing serious ...
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Missing: (β- keto- ethylbenzodioxolylpentanamine- βk- K- EBDP- 727641-67-0
N-Ethylpentylone hydrochloride | C14H20ClNO3 - PubChem
National Institutes of Health (.gov)
https://pubchem.ncbi.nlm.nih.gov › compound
N-Ethylpentylone hydrochloride; S3G8XZW25I; UNII-S3G8XZW25I; 1-Pentanone, 1-(1,3-benzodioxol-5-yl)-2-(ethylamino)-, hydrochloride (1:1); RefChem:163363.
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Missing: keto- ethylbenzodioxolylpentanamine- βk- K- EBDP- ephylone) 727641-67-0
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