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Buy Pheniprazine (Catron) Cas 55-52-7
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Buy Pheniprazine (Catron) Cas 55-52-7

Description

Buy Pheniprazine (Catron) Cas 55-52-7

Pheniprazine, formerly sold under the brand names Catron and Cavodil, is an irreversible and non-selective monoamine oxidase inhibitor (MAOI) of the hydrazine group that was used as an antidepressant to treat depression in the 1960s.[3][4][5][6] It was also used in the treatment of angina pectoris and schizophrenia.[7][8] Pheniprazine has been largely discontinued due to toxicity concerns such as jaundiceamblyopia, and optic neuritis.[9][10][11]

Pharmacology

Pheniprazine is a monoamine oxidase inhibitor (MAOI).[3] Amphetamine has been detected as an active metabolite of pheniprazine in animals.[12] Pheniprazine produces amphetamine- and psychostimulant-like effects at high doses in animals.[13] The same is true of certain other MAOIs, including iproniazidphenelzinetranylcypromine, and pargyline, but not nialamide.[13][14][15]

Chemistry

Pheniprazine, also known as α-methylphenethylhydrazine,[1] is a phenethylamineamphetamine, and hydrazine derivative. It is a close analogue of phenelzine (phenethylhydrazine) and amphetamine (α-methylphenethylamine) and can also be referred to by synonyms including amphetamine hydrazide,[1] α-methylphenelzine, and N-aminoamphetamine. Metfendrazine (α,N-dimethylphenethylhydrazine; N-methylpheniprazine) is the corresponding methamphetamine (N-methylamphetamine) analogue.

Society and culture

Names

Pheniprazine is the generic name of the drug and its INNTooltip International Nonproprietary Name and BANTooltip British Approved Name.[3] It is also known by the former developmental code name JB-516.[3]

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